The Burnham Review

Gluten-Free Happiness, Health, Strength and Endurance

Gluten Sensitivity Gluten-Free Diet
6-23 Reasons to Eliminate Gluten

According to the recent medical literature, people with the following conditions may benefit notably from a gluten-free diet:
- Rheumatoid arthritis
- Multiple sclerosis
- Parkinson’s disease
- Depression
- Neuromyelitis (nervous system inflammation)
- Peripheral neuropathies
- Seizures
- Autism
- Ataxia (loss of balance)
- Late-onset Friedreich ataxia
- Down’s syndrome
- Cognitive problems (brain fog)
- Osteoporosis
- Type 2 and Type 1 diabetes
- Anemia

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Look For These Back Issues

6-21: Disruption of Membrane and Mechanical Tension, The Burnham Review

6-22: Cecum, Large Intestine and Hypertrophy (Cecum H&H), The Burnham Review Nov 2006

6-23: Reasons to Eliminate Gluten, The Burnham Review Dec 2006

6-24: Chemotherapy Side Effects, Manual Therapy and CAM, The Burnham Review Dec 2006

7-01: Benefits of Touch and Neurofascial Process (NFP), The Burnham Review Jan 2007

Highlighted Referecens

1. Jacob, S., M. Zarei, et al. (2005). "Gluten sensitivity and neuromyelitis optica: two case reports." J Neurol Neurosurg Psychiatry 76(7): 1028-30. full article found at:
http://jnnp.bmjjournals.com/cgi/content/full/76/7/1028

2. Elder, J. H., M. Shankar, et al. (2006). "The gluten-free, casein-free diet in autism: results of a preliminary double blind clinical trial." J Autism Dev Disord 36(3): 413-20.

3. Pynnonen, P. A., E. T. Isometsa, et al. (2005). "Gluten-free diet may alleviate depressive and behavioural symptoms in adolescents with coeliac disease: a prospective follow-up case-series study." BMC Psychiatry 5(1): 14 from
http://www.biomedcentral.com/1471-244X/5/14

4. Gale, L., H. Wimalaratna, et al. (1997). "Down's syndrome is strongly associated with coeliac disease." Gut 40(4): 492-6 from
http://gut.bmj.com/cgi/content/abstract/40/4/492

5. Hadjivassiliou, M., Grunewald, R. A., & Davies_Jones, G. A. (2002). Gluten sensitivity as a neurological illness. J Neurol Neurosurg Psychiatry, 72(5), 560_563. from
http://jnnp.bmj.com/cgi/content/extract/72/5/560

6. Wills, A. J., Turner, B., Lock, R. J., Johnston, S. L., Unsworth, D. J., & Fry, L. (2002). Dermatitis herpetiformis and neurological dysfunction. J Neurol Neurosurg Psychiatry, 72(2), 259_261.

Articles References

1. University of Chicago Celiac Disease Program, (2006) from
www.celiacdisease.net/Portals/1/Celiac%20Statistics%20and%20Facts.pdf

2. NIH (2006)
http://digestive.niddk.nih.gov/ddiseases/pubs/celiac/index.htm

3. Weiselfish-Giammatteo, S. and T. Giammatteo (2002). Elimination Diet A New Health Care Tool. Bloomfield, CT, ANA Publishing. from
www.CenterIMT.com

4. Jacob, S., M. Zarei, et al. (2005). "Gluten sensitivity and neuromyelitis optica: two case reports." J Neurol Neurosurg Psychiatry 76(7): 1028-30. full article found at:
http://jnnp.bmjjournals.com/cgi/content/full/76/7/1028

5. Hafstrom, I., B. Ringertz, et al. (2001). "A vegan diet free of gluten improves the signs and symptoms of rheumatoid arthritis: the effects on arthritis correlate with a reduction in antibodies to food antigens." Rheumatology (Oxford) 40(10): 1175-9 from
http://171.66.120.158/cgi/content/abstract/40/10/1175

6. Sokjer, M., T. Jonsson, et al. (1995). "Selective increase of IgA rheumatoid factor in patients with gluten sensitivity." Acta Derm Venereol 75(2): 130-2.

7. Teppo, A. M. and C. P. Maury (1984). "Antibodies to gliadin, gluten and reticulin glycoprotein in rheumatic diseases: elevated levels in Sjogren's syndrome." Clin Exp Immunol 57(1): 73-8.

8. Ivarsson, A. (2005). "The Swedish epidemic of coeliac disease explored using an epidemiological approach--some lessons to be learnt." Best Pract Res Clin Gastroenterol 19(3): 425-40.

9. Woodward, A. B. (2007). "All in your head." Living Without Winter

10. Elder, J. H., M. Shankar, et al. (2006). "The gluten-free, casein-free diet in autism: results of a preliminary double blind clinical trial." J Autism Dev Disord 36(3): 413-20.

11. Kidd, P. M. (2002). "Autism, an extreme challenge to integrative medicine. Part 2: medical management." Altern Med Rev 7(6): 472-99. from
www.findarticles.com

12. Pynnonen, P. A., E. T. Isometsa, et al. (2005). "Gluten-free diet may alleviate depressive and behavioural symptoms in adolescents with coeliac disease: a prospective follow-up case-series study." BMC Psychiatry 5(1): 14 from
http://www.biomedcentral.com/1471-244X/5/14

13. Anheim, M., B. Degos, et al. (2006). "[Ataxia associated with gluten sensitivity, myth or reality?]." Rev Neurol (Paris) 162(2): 214-21.

14. Hadjivassiliou, M., M. Maki, et al. (2006). "Autoantibody targeting of brain and intestinal transglutaminase in gluten ataxia." Neurology 66(3): 373-7.

15. Ihara, M., F. Makino, et al. (2006). "Gluten sensitivity in Japanese patients with adult-onset cerebellar ataxia." Intern Med 45(3): 135-40. from
www.jstage.jst.go.jp/article/internalmedicine/45/3/45_135/_article

16. Wills, A., R. Dale, et al. (2005). "Gluten Ataxia and Post-Streptococcal Central Nervous System Syndromes: Emerging Immune-mediated Disorders of the Central Nervous System?" Curr Treat Options Neurol 7(3): 183-189.

17. Boublik, J. H., M. J. Quinn, et al. (1983). "Coffee contains potent opiate receptor binding activity." Nature 301(5897): 246-8. from
www.nature.com/nature/journal/v301/n5897/abs/301246a0.html

18. Kalaydjian, A. E., W. Eaton, et al. (2006). "The gluten connection: the association between schizophrenia and celiac disease." Acta Psychiatr Scand 113(2): 82-90.

19. Verbeke, S., S. Cruchet, et al. (2004). "[Risk markers for insulin-dependent diabetes mellitus and duration of exposure to gluten in celiac patients]." Rev Med Chil 132(8): 979-84.

20. Pastore, M. R., E. Bazzigaluppi, et al. (2003). "Six months of gluten-free diet do not influence autoantibody titers, but improve insulin secretion in subjects at high risk for type 1 diabetes." J Clin Endocrinol Metab 88(1): 162-5 from
http://jcem.endojournals.org/cgi/content/abstract/88/1/162

21. Hansen, D., B. Brock-Jacobsen, et al. (2006). "Clinical benefit of a gluten-free diet in type 1 diabetic children with screening-detected celiac disease: a population-based screening study with 2 years' follow-up." Diabetes Care 29(11): 2452-6

22. Fiore, C. E., P. Pennisi, et al. (2006). "Altered osteoprotegerin / RANKL ratio and low bone mineral density in celiac patients on long-term treatment with gluten-free diet." Horm Metab Res 38(6): 417-22.

23. Pazianas, M., G. P. Butcher, et al. (2005). "Calcium absorption and bone mineral density in celiacs after long term treatment with gluten-free diet and adequate calcium intake." Osteoporos Int 16(1): 56-63.

24. Solomons, N. W., I. H. Rosenberg, et al. (1976). "Zinc nutrition in celiac sprue." Am J Clin Nutr 29(4): 371-5 from
http://www.ajcn.org/cgi/content/abstract/29/4/371

25. Crofton, R. W., P. J. Aggett, et al. (1990). "Zinc metabolism in celiac disease." Am J Clin Nutr 52(2): 379-82 from
www.ajcn.org/cgi/content/abstract/52/2/379

26. Kanavin, O., H. Scott, et al. (1988). "Immunological studies of patients with Down's syndrome. Measurements of autoantibodies and serum antibodies to dietary antigens in relation to zinc levels." Acta Med Scand 224(5): 473-7.

General References (Many of the Full Articles are Available)

1. Araujo, J., G. A. Silva, et al. (2006). "Prevalence of celiac disease in children and adolescents with type 1 diabetes - Authors' reply." J Pediatr (Rio J)82(5): 401 from
www.scielo.br and http://content.nejm.org/cgi/content/abstract/348/25/2517

2. Bowling (2003) Current Complementary and Alternative Therapies for Multiple Sclerosis

3. Burnham, K (2007) Benefits of a Gluten-Free Diet, Suite 101, from
www.suite101.com/profile.cfm/KimBurnham

4. Casellas, F., J. Lopez Vivancos, et al. (2006). "Current epidemiology and accessibility to diet compliance in adult celiac disease." Rev Esp Enferm Dig98(6): 408-19 from
www.ncbi.nlm.nih.gov

5. Crofton, R. W., S. C. Glover, et al. (1983). "Zinc absorption in celiac disease and dermatitis herpetiformis: a test of small intestinal function." Am J Clin Nutr38(5): 706-12 from
www.ajcn.org/cgi/content/abstract/38/5/706

6. Crofton, R. W., P. J. Aggett, et al. (1990). "Zinc metabolism in celiac disease." Am J Clin Nutr52(2): 379-82 from
www.ajcn.org/cgi/content/abstract/52/2/379

7. Douglass, C., K. Suvarna, et al. (2006). "A novel amyloidogenic transthyretin variant Gly53Ala associated with intermittent headaches and ataxia." J Neurol Neurosurg Psychiatry: from
http://jnnp.bmj.com/cgi/content/abstract/78/2/193

8. Gale, L., H. Wimalaratna, et al. (1997). "Down's syndrome is strongly associated with coeliac disease." Gut40(4): 492-6 from
http://gut.bmj.com/cgi/content/abstract/40/4/492

9. Gautreaux, M. D., E. A. Deitch, et al. (1994). "T lymphocytes in host defense against bacterial translocation from the gastrointestinal tract." Infect Immun62(7): 2874-84 from
www.ncbi.nlm.nih.gov/entrez/query.fcgi

10. Gibbons, C. H. and R. Freeman (2005). "Autonomic neuropathy and coeliac disease." J Neurol Neurosurg Psychiatry76(4): 579-81 from
http://jnnp.bmj.com/cgi/content/full/76/4/579

11. Giovenale, D., C. Meazza, et al. (2006). "The prevalence of growth hormone deficiency and celiac disease in short children." Clin Med Res4(3): 180-3 from
www.clinmedres.org/cgi/content/full/4/3/180

12. Hadjivassiliou, M., Chattopadhyay, A. K., Davies_Jones, G. A., Gibson, A., Grunewald, R. A., & Lobo, A. J. (1997). Neuromuscular disorder as a presenting feature of coeliac disease. J Neurol Neurosurg Psychiatry, 63(6), 770_775. from
http://jnnp.bmj.com/cgi/content/full/63/6/770

13. Hadjivassiliou, M., Grunewald, R. A., & Davies_Jones, G. A. (1999). Gluten sensitivity: a many headed hydra. BMJ, 318(7200), 1710_1711.
www.bmj.com/cgi/content/extract/318/7200/1710

14. Hadjivassiliou, M., Grunewald, R. A., & Davies_Jones, G. A. (2002). Gluten sensitivity as a neurological illness. J Neurol Neurosurg Psychiatry, 72(5), 560_563. from
http://jnnp.bmj.com/cgi/content/extract/72/5/560

15. Hadjivassiliou, M., Grunewald, R., Sharrack, B., Sanders, D., Lobo, A., Williamson, C., et al. (2003). Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics. Brain, 126(Pt 3), 685_691. from
http://brain.oxfordjournals.org/cgi/content/abstract/126/3/685

16. Hadjivassiliou, M., D. S. Sanders, et al. (2004). "Gluten sensitivity masquerading as systemic lupus erythematosus." Ann Rheum Dis63(11): 1501-3 from
http://ard.bmj.com/cgi/content/full/63/11/1501

17. Hadjivassiliou, M., Kandler, R. H., Chattopadhyay, A. K., Davies_Jones, A. G., Jarratt, J. A., Sanders, D. S., et al. (2006). Dietary treatment of gluten neuropathy. Muscle Nerve, 34(6), 762_766. from
http://jnnp.bmj.com/cgi/content/abstract/74/9/1221

18. Hafstrom, I., B. Ringertz, et al. (2001). "A vegan diet free of gluten improves the signs and symptoms of rheumatoid arthritis: the effects on arthritis correlate with a reduction in antibodies to food antigens." Rheumatology (Oxford)40(10): 1175-9 from
http://171.66.120.158/cgi/content/abstract/40/10/1175

19. Hansen, D., B. Brock-Jacobsen, et al. (2006). "Clinical benefit of a gluten-free diet in type 1 diabetic children with screening-detected celiac disease: a population-based screening study with 2 years' follow-up." Diabetes Care29(11): 2452-6 from
http://care.diabetesjournals.org/cgi/content/abstract/29/11/2452

20. Holtmeier, W. and W. F. Caspary (2006). "Celiac disease." Orphanet J Rare Dis1: 3 from
www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pmc.

21. Ihara, M., F. Makino, et al. (2006). "Gluten sensitivity in Japanese patients with adult-onset cerebellar ataxia." Intern Med45(3): 135-40 from
www.jstage.jst.go.jp

22. Jacob, S., M. Zarei, et al. (2005). "Gluten sensitivity and neuromyelitis optica: two case reports." J Neurol Neurosurg Psychiatry76(7): 1028-30 from
http://jnnp.bmj.com/cgi/content/abstract/76/7/1028

23. Kagnoff, M. F. (2007). Celiac disease: pathogenesis of a model immunogenetic disease. J Clin Invest, 117(1), 41_49. from
www.jci.org/cgi/content/abstract/117/1/41

24. Kalaydjian, A. E., Eaton, W., Cascella, N., & Fasano, A. (2006). The gluten connection: the association between schizophrenia and celiac disease. Acta Psychiatr Scand, 113(2), 82_90.

25. Kaminsky, L. S., & Zhang, Q. Y. (2003). The small intestine as a xenobiotic_metabolizing organ. Drug Metab Dispos, 31(12), 1520_1525 from
http://dmd.aspetjournals.org/cgi/reprint/31/12/1520

26. Kidd, P. M. (2002). Autism, an extreme challenge to integrative medicine. Part: 1: The knowledge base. Altern Med Rev, 7(4), 292_316. from
http://findarticles.com/p/articles/mi_m0FDN/is_6_7/ai_96416601

27. Kidd, P. M. (2002). Autism, an extreme challenge to integrative medicine. Part 2: medical management. Altern Med Rev, 7(6), 472_499

28. Kopecny, J., Mrazek, J., Fliegerova, K., & Kott, T. (2006). Effect of gluten_free diet on microbes in the colon. Folia Microbiol (Praha), 51(4), 287_290. from
www.cssm.info/priloha/fm2006_287.pdf

29. Lernmark, A. (2001). Autoimmune diseases: are markers ready for prediction? J Clin Invest, 108(8), 1091_1096. from
www.jci.org/cgi/content/full/108/8/1091

30. Luostarinen, L., Himanen, S. L., Luostarinen, M., Collin, P., & Pirttila, T. (2003). Neuromuscular and sensory disturbances in patients with well treated coeliac disease. J Neurol Neurosurg Psychiatry, 74(4), 490_494. from
http://jnnp.bmj.com/cgi/content/abstract/74/4/490

31. Norris, J. M., Barriga, K., Hoffenberg, E. J., Taki, I., Miao, D., Haas, J. E., et al. (2005). Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. Jama, 293(19), 2343_2351. from
http://jama.highwire.org/cgi/content/abstract/293/19/2343

32. Pastore, M. R., E. Bazzigaluppi, et al. (2003). "Six months of gluten-free diet do not influence autoantibody titers, but improve insulin secretion in subjects at high risk for type 1 diabetes." J Clin Endocrinol Metab88(1): 162-5 from
http://jcem.endojournals.org/cgi/content/abstract/88/1/162

33. Pavlovic, M. D. (2006). Dermatitis herpetiformis presenting as intertriginous dermatitis. Acta Dermatovenerol Alp Panonica Adriat, 15(1), 52_54.

34. Pazianas, M., Butcher, G. P., Subhani, J. M., Finch, P. J., Ang, L., Collins, C., et al. (2005). Calcium absorption and bone mineral density in celiacs after long term treatment with gluten_free diet and adequate calcium intake. Osteoporos Int, 16(1), 56_63. from
www.springerlink.com/content/5na8pjc5r207amvw/resource_secured/?target=fulltext.pdf

35. Pengiran Tengah, D. S., Wills, A. J., & Holmes, G. K. (2002). Neurological complications of coeliac disease. Postgrad Med J, 78(921), 393_398. from
http://pmj.bmj.com/cgi/content/full/78/921/393

36. Pynnonen, P. A., E. T. Isometsa, et al. (2005). "Gluten-free diet may alleviate depressive and behavioural symptoms in adolescents with coeliac disease: a prospective follow-up case-series study." BMC Psychiatry5(1): 14 from
www.biomedcentral.com/1471-244X/5/14

37. Rodrigo, L. (2006). Celiac disease. World J Gastroenterol, 12(41), 6585_6593 from
www.wjgnet.com/1007_9327/12/6585.asp

38. Solomons, N. W., I. H. Rosenberg, et al. (1976). "Zinc nutrition in celiac sprue." Am J Clin Nutr29(4): 371-5 from
www.ajcn.org/cgi/content/abstract/29/4/371.

39. Somay, G., Cevik, D. M., Halac, G. U., Abut, E., & Erenoglu, N. Y. (2005). Cobalamine deficiency associated with neuropathy and oral mucosal melanosis in untreated gluten_sensitive enteropathy. Indian J Gastroenterol, 24(3), 120_122. from
www.indianjgastro.com

40. Tollefsen, S., Arentz_Hansen, H., Fleckenstein, B., Molberg, O., Raki, M., Kwok, W. W., et al. (2006). HLA_DQ2 and _DQ8 signatures of gluten T cell epitopes in celiac disease. J Clin Invest, 116(8), 2226_2236.

41. Wilkinson, I. D., Hadjivassiliou, M., Dickson, J. M., Wallis, L., Grunewald, R. A., Coley, S. C., et al. (2005). Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia. J Neurol Neurosurg Psychiatry, 76(7), 1011_1013 from
http://jnnp.bmj.com/cgi/content/full/76/7/1011

42. Wills, A., Dale, R., & Giovannoni, G. (2005). Gluten Ataxia and Post_Streptococcal Central Nervous System Syndromes: Emerging Immune_mediated Disorders of the Central Nervous System? Curr Treat Options Neurol, 7(3), 183_189.from
www.treatment_options.com/1092_8480/7/183

43. Wills, A. J., Turner, B., Lock, R. J., Johnston, S. L., Unsworth, D. J., & Fry, L. (2002). Dermatitis herpetiformis and neurological dysfunction. J Neurol Neurosurg Psychiatry, 72(2), 259_261.

44. Woodward, A. B. (2007). All in your head. Living Without, Winter.

Web Sites  for additional details about celiac disease (compiled with the help of Anne Howard, PT)

1. Against The Grain
www.angelhealingcenter.com/GlutenIntolerance.html

2. Burnham, K (2007) Benefits of a Gluten-Free Diet, Suite 101, from www.suite101.com/profile.cfm/KimBurnham

3. Café Gratitude Recipe Book, a most amazing restaurant - raw vegan, gluten-free dairy-free, non-genetically modified, no processed sugar and all the food is delicious and satisfying
www.withthecurrent.com/cafe.html

4. Celiac Disease Foundation.
www.celiac.org/  

5. Celiac Sprue Association
www.csaceliacs.org

6. Celiac Sprue
http://members.ozemail.com.au/~coeliac/sprue.html

7. Celiac Disease Foundation
www.celiac.org

8. Celiac Disease Center at Columbia College
www.celiacdiseasecenter.columbia.edu

9. Celiac/Coeliac, Dermatitis Herpetiformis, Wheat/Gluten-Free
www.enabling.org/ia/celiac/index.html  

10 Celiac Sprue Association
www.csaceliacs.org/  

11. EnteroLab, site that will do a stool test (no physician referral required) for gluten, dairy, egg, yeast, and soy. Also does a cheek swab DNA gene analysis to determine if you have the celiac genes or gluten sensitivity genes. Good to measure your degree of gut irritation/dysfunction
www.enterolab.com/

12. Gluten Intolerance Group
www.gluten.net

\13. Gluten Free Casein Free Food
www.gfcfdiet.com

14. Gluten Intolerance Group of North America, a good 2 page brochure on the differences between celiac and gluten-sensitive enteropathy and basic frequently asked questions (FAQ).
www.gluten.net/downloads/infopackets/GlutenIntolnotCD.pdf

15. Celiac.com, a great multi-purpose site, including basic information and links to recent relevant medical findings on celiac disease and gluten sensitivity.
www.celiac.com

16. Gluten Freedom
www.glutenfreedom.net/page.asp?itemid=12

17. Gluten Reactivity, a good site with a lot of education, designed for the undiagnosed person wondering how to manage the testing and change of diet.
www.glutensensitivity.net/

18. Gluten-Free Links, Celiac Disease/Gluten Intolerance Web Sites
www.gflinks.com

19. Gluten-Free Works
www.glutenfreeworks.com/gluteninformation.php

20. Gluten-Free
www.glutenfree.com/

21. Kinnikinnick Foods Inc
www.kinnikinnick.com

22. Melissa Diane Smith
www.melissadianesmith.com/Articles/GlutenSensitivityDerailingHealth.html  

23. National Foundation for Celiac Awareness
www.celiaccentral.org/  

24. Public Medline
www.ncbi.nlm.nih.gov

25. Shop by Diet, a great website that will list foods by your dietary needs, allowing you to filter their entire online store by gluten free, dairy-free, peanut-free, or whatever restrictions you are currently needing.
www.shopbydiet.com

26. University of Chicago Celiac Disease Program
www.celiacdisease.net

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