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Integrative Medicine & Manual Therapy Research for Health, Healing & Quality of Life
 
Infectious Disorders
8-10 Infectious Disorders and Integrative Manual Therapy

Infectious Disorders Course Powerpoint

Consciousness, Connective Tissue Blueprints and MicroTubules
    A newly proposed physical phenomenon of quantum wave function "self-collapse"(objective reduction: OR -Penrose, 1994) are essential for consciousness, and occur in cytoskeletal microtubules and other structures within each of the brain's neurons
    Link between Consciousness and Microtubules (Connective Tissue Blueprints)

Inner Life of Cells Movies - Great Visuals

Avian Flu and Osteopathic Medicine
    Avian influenza is an infection caused by the H5N1 virus. 
    There is a fear is that a pandemic of avian influenza could result in the kind of mortality that was seen with the Spanish influenza pandemic of 1918-1919, where the number of deaths was estimated to be as high as 40 million people. 
    Retrospective data gathered by the American Osteopathic Association shortly after the 1918-1919 influenza pandemic have suggested that osteopathic physicians (DOs), using their distinctive osteopathic manipulative treatment (OMT) methods, observed significantly lower morbidity and mortality among their patients as compared to those treated by allopathic physicians (MDs) with standard medical care available at the time. OMT procedures that could be utilized as part of the treatment protocol for avian influenza patients.(Hruby,2007). Hruby, R. J. and K. N. Hoffman (2007). "Avian influenza: an osteopathic component to treatment." Osteopath Med Prim Care 1: 10 [Full Text] www.om-pc.com/content/1/1/10.

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7-1 Benefits of Touch and NFP, The Burnham Review    FREE Today

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Immune System 8-21:
Lyme Disease, Borreliosis and Extracellular Matrix, The Burnham Reivew

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Infectious Disorders, The Burnham Review

8-10: Influenza, Bird Flu and Osteopathy, The Burnham Review

Media That Matters Film Festival: The Luckiest Nut In The World: About A singing peanut and his gang of shelled friends explain that sometimes free trade is just nuts. Luckiest Nut

Homotoxicology Chart

Sanum Pleomorphics
    
Therapy with good prospects using SANUKEHLs: A broad spectrum of effects from hapten remedies by Dr. Konrad Werthmann, Austria

General References

[PubMed Abstracts]
http://www.ncbi.nlm.nih.gov

1. ------ (2007). "Lyme Natural Health Care." [Full Text] http://health.groups.yahoo.com/group/lyme-naturalhealthcare/.
    Herbs, energetic methods, ozone, homeopathy, oxygen, sanum remedies, neurotransmitter balancing, parasympathetic recovery, detox, support, building emotionally and physically, color, chi gong, meditation, scenar, LED and laser, Heavy Metal protocols,etc

2. ------ (2007). "Lyme Disease Remedies." The New England Journal of Homeopathy: [Reference] http://www.nesh.com.
    Remedies for Lyme Disease: Mercurius, Lachesis, Spigelia, Euphorbium, Natrum muriaticum , Apis from
Vol 7 #1 Lyme Disease Lyme with the Desire to Kill Rotundo, Beth Case Mercurius
Vol 7 #1 Lyme Disease A Subacute Case of Lyme Disease Guess, George MD DHt Case Lachesis
Vol 7 #1 Lyme Disease Trigeminal Neuralgia and Palpitations from Lyme Disease Fine, Howard ND Case Spigelia
Vol 7 #1 Lyme Disease A Small Remedy in (Alleged) Lyme Disease in a Dog Levy, Jeff DVM Case / Vet Homeo. Euphorbium
Vol 9 #2 Lyme Disease If you Hear Hoofbeats, Don't Think Zebras - A Case of Chronic Lyme Disease Rothenberg, Amy ND DHANP Case Natrum muriaticum
Vol 7 #1 Lyme Disease / Diarrhea Ticked Off by a Tick Malerba, Larry DO Case Apis
Vol 7 #1 Lyme Disease / Neuralgia A Case of a Lyme Related Neuropathy Malerba, Larry DO Case Spigelia

3. Bransfield, R. C., J. S. Wulfman, et al. (2007). "The association between tick-borne infections, Lyme borreliosis and autism spectrum disorders." Med Hypotheses. [Full Text] http://www.lymeinducedautism.com/images/TBILB_Autism.pdf
    Chronic infectious diseases, including tick-borne infections such as Borrelia burgdorferi may have direct effects, promote other infections and create a weakened, sensitized and immunologically vulnerable state during fetal development and infancy leading to increased vulnerability for developing autism spectrum disorders. A dysfunctional synergism with other predisposing and contributing factors may contribute to autism spectrum disorders by provoking innate and adaptive immune reactions to cause and perpetuate effects in susceptible individuals that result in inflammation, molecular mimicry, kynurenine pathway changes, increased quinolinic acid and decreased serotonin, oxidative stress, mitochondrial dysfunction and excitotoxicity that impair the development of the amygdala and other neural structures and neural networks resulting in a partial Kluver-Bucy Syndrome and other deficits resulting in autism spectrum disorders and/or exacerbating autism spectrum disorders from other causes throughout life. Support for this hypothesis includes multiple cases of mothers with Lyme disease and children with autism spectrum disorders; fetal neurological abnormalities associated with tick-borne diseases; similarities between tick-borne diseases and autism spectrum disorder regarding symptoms, pathophysiology, immune reactivity, temporal lobe pathology, and brain imaging data; positive reactivity in several studies with autistic spectrum disorder patients for Borrelia burgdorferi (22%, 26% and 20-30%) and 58% for mycoplasma; similar geographic distribution and improvement in autistic symptoms from antibiotic treatment. It is imperative to research these and all possible causes of autism spectrum disorders in order to prevent every preventable case and treat every treatable case until this disease has been eliminated from humanity. (Bransfield,2007).

4. Cabello, F. C., H. P. Godfrey, et al. (2007). "Hidden in plain sight: Borrelia burgdorferi and the extracellular matrix." Trends Microbiol 15(8): 350-4. [PubMed Abstract] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17600717
    Borrelia burgdorferi, the tick-transmitted etiologic agent of Lyme borreliosis, can colonize and persist in multiple tissue sites despite vigorous host immune responses. The extracellular matrix appears to provide a protective niche for the spirochete. Recent studies in mice suggest that B. burgdorferi interacts in various ways with collagen and its associated molecules, exploiting molecular and structural features to establish microcolonial refugia. Better knowledge of the genetic and structural bases for these interactions of B. burgdorferi with the extracellular matrix will be required before an understanding of the persistence of B. burgdorferi in the tissues and development of chronic infections can be achieved. Center For Complex Infectious Diseases www.ccid.org

5. Craig-Mylius, K., G. F. Weber, et al. (2005). "Borrelia burgdorferi, an extracellular pathogen, circumvents osteopontin in inducing an inflammatory cytokine response." J Leukoc Biol 77(5): 710-8 [Full Text] http://www.jleukbio.org/cgi/content/full/77/5/710.

6. Dommerholt, J. (2007). "Myofascial Trigger Points: An Evidence-Informed Review." Bethesda Physiocare: [Full Text] http://www.bethesdaphysiocare.com/professionals/pdf/jmmt_mtrp-evidencereview_06.pdf
    Clinically, physical therapists should address all aspects of the dysfunction. There are many other conditions that feature muscle pain and MTrPs, including hypothyroidism, systemic lupus erythematosis, Lyme disease, babesiosis, ehrlichiosis, candida albicans infections, myoadenylate deaminase deficiency, hypoglycaemia, and parasitic diseases such as fascioliasis, amoebiasis, and giardia. Therapists should be familiar with the symptoms associated with these medical diagnoses.

7. Foster, J., P. Kane, et al. (2002). "The Detoxx System: Detoxification of Biotoxins in Chronic Neurotoxic Syndromes." Mercola Newsletter: [Full Text] http://findarticles.com/p/articles/mi_m0ISW/is_2002_Nov/ai_93736413.

8. Hodara, S. (2007). "Practitioners striving for innovative options, better treatment, new hope." Special to the Journal News(March 25): [Full Text] www.thejournalnews.com/apps/pbcs.dll/article?AID=/20070325/BUSINESS01/703250302/-1/SPECIAL08
    Hyperbaric Oxygen and Integrative Manual Therapy
It is not the medical profession as a whole that moves health care into the future, but the individual practitioners within it. It is they who explore revolutionary treatments and powerful new drugs, who ennoble patient care and increase the chances that those who are ill will be cured. Driven by personal commitment, these individuals research advances in their fields, and initiate programs and procedures that reflect their knowledge. Their efforts benefit us all.
    Following are five area medical professionals whose pioneering work offers patients of all ages with a variety of health problems new treatment options and new hope.
    Dr. Giuseppina Benincasa-Feingold, Owner, Valley Health, Mahopac
    Ten years ago, when Dr. Giuseppina (Jo) Benincasa-Feingold, an emergency room pediatrician, gave birth to her second daughter, Elisa, her professional path veered toward where it is today. Elisa was born with cerebral palsy, and, Feingold said, "I had to find a way to help her."
    After three years of physical and occupation therapies, Feingold, who by then had had triplets, enrolled Elisa in a cerebral palsy study using hyperbaric oxygen therapy. HBOT is a treatment that saturates the body with oxygen while the patient lies in a cylindrical chamber. Other than ear symptoms similar to those experienced on an airplane, the patient is comfortable, and can spend the one- to two-hour sessions napping or watching television. HBOT is traditionally used for such conditions as carbon monoxide poisoning, decompression sickness, radiation tissue damage, and burns.
    Feingold was struck by the changes in her daughter. "When we started, Elisa spoke about 30 words," she recalled. "We did 120 treatments between December 1999 and April 2000, and by July, her vocabulary had grown to over 1,000 words."
    In 2001, she opened Valley Health, now located in Mahopac, where she uses HBOT to treat an assortment of conditions including cerebral palsy, autism, chronic Lyme disease, chronic fatigue syndrome, migraines and cluster headaches, and brain injuries.

9. Klinghardt, D. (2002). "The Klinghardt Neurotoxin Elimination Protocol." Explore Issue: Volume 12, Number 2: [Full Text] http://www.explorepub.com/articles/summaries/12_2_klinghardt.html
    Biotoxins: such as tetanus toxin, botulinum toxin (botox), ascaridin (from intestinal parasites), unspecified toxins from streptococci, staphylococci, lyme disease, clamydia, tuberculosis, fungal toxins and toxins produced by viruses. Biotoxins are minute molecules (200-1000 kilodaltons) containing nitrogen and sulfur. They belong to a group of chemical messengers which microorganisms use to control the host´s immune system, host behaviour and the host´s eating habits.

10. Klotter, J. (2007). "Lyme Disease." Townsend Letter for Doctors and Patients(April): [Full Text] http://www.townsendletter.com/April2007/shorts0407.htm.

11. Martin, W. J. (2001). "Stealth Viruses." Explore Issue: Volume 10, Number 4: [Full Text] http://www.explorepub.com/articles/martin_10_4.html
    Bacterial sequences incorporated within stealth-adapted viruses may help explain positive findings in stealth virus infected patients in various tests for known bacteria, including Borrelia burgdoferi (the cause of authentic Lyme disease), mycoplasma (a suggested cause of CFS and Gulf War syndrome); chlamydia (implicated in coronary artery disease and Alzheimer's disease), etc. None of the commonly used assays for these bacteria actually detect cultured organisms, but instead rely upon broadly reactive molecular and/or serological testing that could as easily be explained by the presence of viteria.

12. Lunemann, J. D., H. Gelderblom, et al. (2007). "Cerebrospinal fluid-infiltrating CD4+ T cells recognize Borrelia burgdorferi lysine-enriched protein domains and central nervous system autoantigens in early lyme encephalitis." Infect Immun 75(1): 243-51. [Full Text] http://iai.asm.org/cgi/reprint/75/1/243  

13. Martin, W. J. (2002). "Chemokines and Stealth Viruses:A Blueprint for Therapy in Infected Humans and Animals " Explore Issue: Volume 11, Number 1: [Full Text] http://www.explorepub.com/articles/martin_11_1.html.

14. Pancewicz, S. A., R. Rutkowski, et al. (2007). "[Immunopathology of Lyme arthritis]." Pol Merkur Lekarski 23(134): 141-4. [PubMed Abstract] 
    Lyme borreliosis (Lyme disease) is the most prevalent tick-borne disease caused by spirochaetes of the Borrelia species complex. Arthritis is one of the common manifestations of B. burgdorferi infection. The pathomechanism of articular changes in Lyme arthritis has not yet been elucidated. Histopathological studies of synovia and immunological changes are similar to rheumatoid arthritis. In the early stage of inflammation B. burgdorferi interact with polynuclear granulocytes and epithelial cells, triggering production of reactive oxygen species, lipid peroxidation products and other inflammatory mediators. The imbalance between anabolic and catabolic processes in inflamed joints results in the progressive destruction of articular cartilage and disintegration of extracellular matrix. Molecular mimicry between OspA (outer surface protein A) and adhesion molecule LFA-1alpha seems to be responsible for chronic arthritis. (Pancewicz,2007).

15. Raveche, E. S., S. E. Schutzer, et al. (2005). "Evidence of Borrelia autoimmunity-induced component of Lyme carditis and arthritis." J Clin Microbiol 43(2): 850-6. [Full Text] http://jcm.asm.org/cgi/content/full/43/2/850?view=long&pmid=15695691 
    We investigated the possibility that manifestations of Lyme disease in certain hosts, such as arthritis and carditis, may be autoimmunity mediated due to molecular mimicry between the bacterium Borrelia burgdorferi and self-components. We first compared amino acid sequences of Streptococcus pyogenes M protein, a known inducer of antibodies that are cross-reactive with myosin, and B. burgdorferi and found significant homologies with OspA protein. We found that S. pyogenes M5-specific antibodies and sera from B. burgdorferi-infected mice reacted with both myosin and B. burgdorferi proteins by Western blots and enzyme-linked immunosorbent assay. To investigate the relationship between self-reactivity and the response to B. burgdorferi, NZB mice, models of autoimmunity, were infected. NZB mice infected with B. burgdorferi developed higher degrees of joint swelling and higher anti-B. burgdorferi immunoglobulin M cross-reactive responses than other strains with identical major histocompatibility complex (DBA/2 and BALB/c). These studies reveal immunological cross-reactivity and suggest that B. burgdorferi may share common epitopes which mimic self-proteins. These implications could be important for certain autoimmunity-susceptible individuals or animals who become infected with B. burgdorferi. (Raveche,2005).

16. Shelton, B. (2007). "Lyme disease diagnoses and therapy will be litmus test for pleomorphism, Enderlein Sanum therapy." (Dec): [Full Text] www.drbruceshelton.com/index2.php?option=com_content&do_pdf=1&id=28
    Lyme is considered to be the hidden epidemic of our time that is a spirochete caused infection transmitted by a bite from a tick and can present as severe arthritic problems and associated skin rashes. The several blood tests that are used to test for it seem to be positive in 90-100% of patients tested as if it cross reacts immunologically with other germs making it hard to know whether the patient being tested has Lyme disease or something else but which can cause fatal problems if not addressed quickly and aggressively.

17. Schneider, P. (2001). "Prof. Enderlein’s Research in Today’s View: Can his research results be confirmed with modern techniques?" SANUM-Post magazine (56/2001) Semmelweis-Institut GmbH Verlag für experimentelle Onkologie GmbH · 27316 Hoya · Germany: [Full Text] http://www.pferdemedizin.com/peter/enderlein_engl.pdf.

18. Waterhouse, J. C. (2007). "Vitamin D, the Vitamin D Receptor and Chronic Disease -- Brain Lesions, Vascular Calcification and Osteoporosis: Two Views of Vitamin D Supplementation and Parathyroid Hormone " CISRA's Synergy Health Newsletter, Issue 11 --Preview, November 19: [Full Text] http://members.aol.com/SynergyHN/shpt.

19. Waterhouse, J. C. (2007). "The Marshall Protocol for Lyme disease and other chronic inflammatory conditions. I." The Townsend Letter for Doctors and Patients April No. 285: [Full Text] http://winmlm.neostrada.pl/mp/townsend/Townsend_Apr07.PartOne.pdf      

20. Waterhouse, J. C. (2007). "The Marshall Protocol for Lyme disease and other chronic inflammatory conditions II." The Townsend Letter for Doctors and Patients May No. 286: [Full Text]
http://winmlm.neostrada.pl/mp/townsend/Townsend_Letter_May2007.Part2.pdf  

21. Weiselfish-Giammatteo (2005) "Infectious Disorders Course" Connecticut School of Integrative Manual Therapy with Dialogues in Contemporary Rehabilitation. http://www.CenterIMT.com

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